diff --git a/interpreters/quickjs/Makefile b/interpreters/quickjs/Makefile
index eab440a2b..1a916275c 100644
--- a/interpreters/quickjs/Makefile
+++ b/interpreters/quickjs/Makefile
@@ -33,7 +33,7 @@ MAINSRC = qjs.c
 
 VERSION=\"$(shell cat $(QUICKJS_UNPACK)/VERSION)\"
 
-CFLAGS += -DCONFIG_VERSION=$(VERSION) -Wno-shadow -D__NuttX__
+CFLAGS += -DCONFIG_VERSION=$(VERSION) -Wno-shadow
 CFLAGS += -Wno-array-bounds -I$(QUICKJS_UNPACK)
 ifneq ($(CONFIG_INTERPRETERS_QUICKJS_BIGNUM),)
 CFLAGS += -DCONFIG_BIGNUM